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Redington Life Sciences News | Double Issue June 2020 | ||
In this issue: On being fat with COVID, coolest tech in the cancer toolkit, if your microwave could talk, trucks/trailers and Parkinson’s, revisiting vaccines, MIT on boosting I-O therapy, scientists crack nature’s most common bond, Dana-Farber on ancestry and cancer, diet and gut microbes affect chemo outcomes, COVID cost of delaying cancer surgery, and more… | |||
 | Diet, Gut Microbes Affect Chemotherapy Outcomes What we eat can affect the outcome of chemotherapy – and likely many other medical treatments – because of ripple effects that begin in our gut, new research suggests. |
 | Gene discovery in fruit flies 'opens new doors' for hearing loss cure in elderly Scientists have discovered sets of regulatory genes, which are responsible for maintaining healthy hearing. The finding, made in fruit flies, could potentially lead to treatments for age-related hearing loss (ARHL) in humans. |
 | The race for coronavirus vaccines: a graphical guide |
 | A boost for cancer immunotherapy One promising strategy to treat cancer is stimulating the body’s own immune system to attack tumors. However, tumors are very good at suppressing the immune system, so these types of treatments don’t work for all patients. MIT engineers have now come up with a way to boost the effectiveness of one type of cancer immunotherapy. They showed that if they treated mice with existing drugs called check |
 | Large Study Finds No Evidence That Low-dose Aspirin Reduces Alzheimer’s Risk Taking daily low-dose aspirin does not seem to reduce the risk of dementia, cognitive decline, or Alzheimer’s disease , new clinical trial data show. The results were published in Neurology in a study, titled " Randomized placebo-controlled trial of the effects of aspirin on dementia and cognitive decline ." Aspirin is a widely-used anti-inflammatory medication. Among its uses, low-dose daily... |
| Cancer can’t wait: Why some patients may benefit from expedited breast cancer treatments |
 | Southampton scientists discover a "switch" that turns autoimmunity drugs into powerful anti-cancer treatments Scientists from the Antibody and Vaccine group at the University of Southampton have discovered a way to transform antibody drugs previously developed to treat autoimmunity into antibodies with powerful anti-cancer activity through a simple molecular "switch". |
 | Scientists finally crack nature’s most common chemical bond The carbon-hydrogen bond makes up two-thirds of all the bonds in hydrocarbons, yet has defied chemists' attempts to open it up and add new chemical groups. John Hartwig's lab has now cracked that problem. |
NIH releases strategic plan to accelerate nutrition research over next 10 years With a focus on precision nutrition, the plan reflects the wide range of nutrition research supported across the agency. | |
 | Radiologists use deep learning to find signs of COVID-19 in chest X-rays Despite a shortage of available chest X-rays for patients with COVID-19, the team's model correctly identified the infection 89% of the time... |
 | Thousands of lives could be lost to delays in cancer surgery during COVID-19 pandemic Delays to cancer surgery and other treatment caused by the COVID-19 crisis could result in thousands of additional deaths linked to the pandemic in England, a major new study reports. |
 | Scientists find evidence of link between diesel exhaust, risk of Parkinson’s A study in zebrafish identified how air pollutants contribute to the buildup of toxic proteins associated with the disease. |
| Obesity Makes COVID-19 Harder to Fight With so much misinformation surrounding obesity, Catherine Varney, DO, is careful with her words. First of all, she clarifies that her patients are not obese but rather have obesity, which is a disease and not a lack of willpower. What is clear: Obesity makes people sick and makes it harder to fight COVID-19. "Obesity is the […] |
| Scientists find a switch to flip and turn off breast cancer growth and metastasis Researchers have identified a gene that causes an aggressive form of breast cancer to rapidly grow. More importantly, they have also discovered a way to ''turn it off'' and inhibit cancer from occurring. The animal study results have been so compelling that the team is now working on FDA approval to begin clinical trials.
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Emergency drug overdose visits associated with increased risk for later suicide NIH-funded study highlights importance of emergency department-based interventions for mitigating suicide risk.
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| Cryo-electron microscopy – the coolest tech in the cancer toolkit Cryo-electron microscopy is an exciting technology that could revolutionise drug design by seeing complex molecules in unprecedented detail. The Institute of Cancer Research has been at the vanguard in applying it to cancer – and now a new collaboration called the London Consortium for Cryo-EM (LonCEM) is using this super-cooled technique to learn more about the mechanisms of life and cancer. |
 | Does estrogen influence alcohol use disorder? A new study from researchers at the University of Illinois at Chicago shows that high estrogen levels may make alcohol more rewarding to female mice. The study, published in the Journal of Neuroscience, suggests that treatment for alcohol use disorder or binge drinking behavior may be more effective if sex differences are considered. |
| What can your microwave tell you about your health? For many of us, our microwaves and dishwashers aren’t the first thing that come to mind when trying to glean health information, beyond that we should (maybe) lay off the Hot Pockets and empty the dishes in a timely way. But we may soon be rethinking that, thanks to new research from MIT’s Computer Science and Artificial Intelligence Laboratory (CSAIL). The system, called "Sapple," analyzes... |
| UCLA scientists alter genes of innate immune cells with DNA-snipping tool The blood cells, part of the body's first line of defense against infection, have been notoriously difficult to genetically engineer. |
 | Study takes most comprehensive look to date at connection between the ancestry and the molecular makeup of cancer A new paper by researchers from the NCI Cancer Genome Analysis Network, a collaborative group with investigators in the U.S., Canada and Europe, provides the most comprehensive look to date at the effect of ancestry on the molecular makeup of normal and cancerous tissues. |
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