An ion channel called TRPC5 acts as a molecular cold sensor in teeth and could serve as a new drug target for treating toothaches.
Redington Life Sciences News
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Special Issue April 2021 |
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In this issue: How teeth sense cold, new treatments for ‘silent’ stroke, Dana Farber on kidney cancer, Mayo on pregnancy and Covid-19 vaccines, new Alzheimer’s genes discovered, if you’re pregnant—exercise!, NIH on youthful cannabis use, dysfunction in a brainy node, reading minds with ultrasound, Yale on eating disorders, narcissism driven by insecurity, salt scans and cancer, can cancer develop in the heart?, and more… |
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Mysteries of malaria infections deepen after human trial study Scientists have discovered that tracking malaria as it develops in humans is a powerful way to detect how the malaria parasite causes a range of infection outcomes in its host. The study, found some remarkable differences in the way individuals respond to malaria and raises fresh questions in the quest to understand and defeat the deadly disease. |
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An ion channel called TRPC5 acts as a molecular cold sensor in teeth and could serve as a new drug target for treating toothaches. |
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Newly discovered node in brain could expand understanding of dysfunctional social behavior |
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New genetic clues point to new treatments for ‘silent’ stroke Researchers discovered changes to 12 genetic regions in the DNA of people who have had a lacunar stroke – a type of stroke caused by weakening of the small blood vessels deep within the brain. Over time, damage to the blood vessels and subsequent interruption to blood flow can lead to long-term disability, causing difficulty with thinking, memory, walking and ultimately dementia. |
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Dana-Farber research leads to better understanding of the immune system in kidney cancer Two Dana-Farber research papers highlight single-cell dissection of kidney tumors to identify new immunotherapy treatments and targets |
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Tonix Pharmaceuticals Reports Positive COVID-19 Vaccine Efficacy Results in Non-Human Primates Vaccinated with TNX-1800 and Challenged with Live SARS-CoV-2 TNX-1800 is Based on a Proprietary Vaccine Platform Designed to Stimulate Long Term T cell ImmunityVaccine Candidate TNX-1800 Protected Both Upper and Lower Airways After Challenge with SARS-CoV-2, Suggesting an Ability to Block Forward TransmissionFull Details |
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Thirteen new Alzheimer's genes identified in human genome study Prior known Alzheimer's genes have been associated with amyloid accumulation and neuroinflammation. A cutting-edge technique known as whole genome sequencing was used to identify new, rare gene variants associated with Alzheimer's disease. Findings could suggest new targets for drug development aimed at enhancing neuroplasticity and the stability of synapses. Full Details |
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Mysterious 'nuclear speckle' structures inside cells enhance gene activity, may help block cancers Scientists has illuminated the functions of mysterious structures in cells called 'nuclear speckles,' showing that they can work in partnership with a key protein to enhance the activities of specific sets of genes. Full Details |
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Narcissism driven by insecurity, not grandiose sense of self Narcissism is driven by insecurity, and not an inflated sense of self, finds a new study, which may also explain what motivates the self-focused nature of social media activity. |
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Reading minds with ultrasound: A less-invasive technique to decode the brain's intentions
A new brain imaging application uses ultrasound to predict intended movements before they happen. |
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Babies prefer baby talk, whether they're learning one language or two A study finds babies prefer baby talk, whether they're learning one language or two. Scientists knew infants learning one language preferred the sing-song tones of parents' baby talk, and now scientists have found babies learning two languages are developmentally right on track. Bilingual babies showed the same interest in baby talk, at the same age, as monolingual babies. |
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New study links protein causing Alzheimer’s disease with common sight loss Newly published research has revealed a close link between proteins associated with Alzheimer’s disease and age-related sight loss. The findings could open the way to new treatments for patients with deteriorating vision and through this study, the scientists believe they could reduce the need for using animals in future research into blinding conditions. |
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The Deadly Lung Disease You've Probably Never Heard Of Pulmonary fibrosis is diagnosed in about 50,000 new patients annually, and as many as 40,000 Americans die from it each year |
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Double duty: Gut’s immune system helps regulate food processing, too Yale researchers report the critical role played by the gut’s immune system in absorbing crucial nutrients to life and warding off life-threatening bacteria. |
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Researchers find a better way to measure consciousness Millions of people are administered general anesthesia each year in the United States alone, but it’s not always easy to tell whether they are actually unconscious. A small proportion of those patients regain some awareness during medical procedures, but a new study of the brain activity that represents consciousness could prevent that potential trauma. |
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‘Leap forward’ in risk management of rectal cancer Images from a probe, combined with deep learning, better differentiated residual cancerous tissue from recovered healthy tissue after chemoradiation treatment |
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Mayo Clinic Minute: Understanding chronic kidney disease |
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What studies show about pregnancy, COVID-19 vaccines A recent data review by the Advisory Committee on Immunization Practices shows that over 30,000 women who are pregnant have been safely vaccinated for COVID-19. The preliminary safety study, which took place between December 2020 and January 2021, compared women who were pregnant and not pregnant, and who received the Pfizer or Moderna COVID-19 vaccines. |
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Science Surgery: ‘Can cancers develop in the heart?’ Science blog Our Science Surgery series answers your cancer questions. Cancer can develop in nearly every organ in the body, including vital organs like the brain and lungs. As organs go, the heart is pretty vital – it’s basically one big muscle whose purpose is to pump blood around our bodies. |
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Most people only have to contract the flu once to be convinced that skipping a vaccination the next season isn’t a good idea. Cheers to those who choose to avoid the flu, or at least sidestep a full assault, by getting vaccinated before contracting and spreading it. Full Details |
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